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The mesonephric duct, also known as the Wolffian duct, archinephric duct, Leydig's duct or nephric duct, is a paired organ that develops in the early stages of embryonic development in humans and other mammals. It is an important structure that plays a critical role in the formation of male reproductive organs.
m, m. Right and left Müllerian ducts uniting together and running with the Wolffian ducts in gc, the genital cord. ot. The genital ridge from which either the ovary or testis is formed. ug. Sinus urogenitalis. W. Left Wolffian body. w, w. Right and left Wolffian ducts. B.—Diagram of the female type of sexual organs.
During this time, the single-layered paramesonephric duct epithelium differentiates into other structures, ranging from the ciliated columnar epithelium in the uterine tube to stratified squamous epithelium in the vagina. [8] The paramesonephric ducts and the mesonephric ducts share a majority of the same mesenchyme due to Hox gene expression.
The Müllerian ducts are also referred to as paramesonephric ducts, referring to ducts next to (para) the mesonephric (Wolffian) duct during foetal development. Paramesonephric ducts are paired ducts derived from the embryo, and for females develop into the uterus, uterine tubes, cervix and upper two-thirds of the vagina. [6]
Right and left Müllerian ducts uniting together and running with the Wolffian ducts in gc, the genital cord m. Müllerian duct , the upper part of which remains as the hydatid of Morgagni ; the lower part, represented by a dotted line descending to the prostatic utricle , constitutes the occasionally existing cornu and tube of the uterus ...
The fetus has two sets of tubes which give rise to accessory reproductive organs - the (Wolffian) mesonephric ducts and the (Müllerian) paramesonephric ducts. Usually, the Wolffian duct gives rise to male reproductive organs (specifically the testicle, epididymis and vas deferens) while the Müllerian to female (the fallopian tubes, the uterus ...
Embryos are formed with Wolffian and Mullerian ducts, which will either become the male or female reproductive tract, respectively. [8] In a male embryo, the testicular cords will induce the development of the Wolffian duct into the vas deferens, epididymis and the seminal vesicle and cause the repression and regression of the Mullerian duct. [4]
The ducts pass backward lateral to the Wolffian ducts, but toward the posterior end of the embryo they cross to the medial side of these ducts, and thus come to lie side by side between and behind the latter—the four ducts forming what is termed the common genital cord, to distinguish it from the genital cords of the germinal epithelium seen ...