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Pantoprazole, sold under the brand name Protonix, among others, is a medication used for the treatment of stomach ulcers, short-term treatment of erosive esophagitis due to gastroesophageal reflux disease (GERD), maintenance of healing of erosive esophagitis, and pathological hypersecretory conditions including Zollinger–Ellison syndrome.
epocrates is a widely used mobile medical reference application that provides healthcare professionals with access to clinical information at the point of care. The software is designed to assist physicians, pharmacists, nurse practitioners, physician assistants and other healthcare providers in making informed decisions about drug interactions, medical calculations, diagnosis and treatment ...
[55] [57] An interaction between PPIs and the metabolism of the platelet inhibitor clopidogrel is known and this drug is also often used in people with cardiac disease. [ 58 ] [ 59 ] [ 22 ] There are associations with an increased risk of stroke, but this appears to be more likely to occur in people who already have an elevated risk.
Pantoprazole obtained high selection criteria in its development process — especially concerning the favorable low potential for interaction with other drugs. Good solubility of pantoprazole and a very high solution stability allowed it to become the first marketed PPI for intravenous use in critical care patients.
The number of notable protein-ligand docking programs currently available is high and has been steadily increasing over the last decades. The following list presents an overview of the most common notable programs, listed alphabetically, with indication of the corresponding year of publication, involved organisation or institution, short description, availability of a webservice and the license.
In pharmaceutical sciences, drug interactions occur when a drug's mechanism of action is affected by the concomitant administration of substances such as foods, beverages, or other drugs. A popular example of drug–food interaction is the effect of grapefruit on the metabolism of drugs .
"Indiana University Department of Medicine Clinical Pharmacology Drug Interactions Flockhart Table ™". "INHIBITORS, INDUCERS AND SUBSTRATES OF CYTOCHROME P450 ISOZYMES". "The Life Raft Group: Long List of Inhibitors and Inducers of CYP3A4 and CYP2D6". "DRUGBANK Online: Cytochrome P-450 Enzyme Inhibitors".
CSP: Communicating sequential processes; formal language for describing patterns of interaction in concurrent systems. FDR2 is a refinement checking tool for CSP, comparing two models for compatibility. DVE input language: a system is described as Network of Extended Finite State Machines communicating via shared variables and unbuffered channels.