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Dr. Dean's research on the fluoride-dental caries relationship, published in 1942, included 7,000 children from 21 cities in Colorado, Illinois, Indiana, and Ohio. The study concluded that the optimal amount of fluoride which minimized the risk of severe fluorosis but had positive benefits for tooth decay was 1 mg per day, per adult.
Referring to a common salt of fluoride, sodium fluoride (NaF), the lethal dose for most adult humans is estimated at 5 to 10 g (which is equivalent to 32 to 64 mg elemental fluoride/kg body weight). [ 2 ] [ 3 ] [ 4 ] Ingestion of fluoride can produce gastrointestinal discomfort at doses at least 15 to 20 times lower (0.2–0.3 mg/kg or 10 to 15 ...
Building on these findings, a 2025 JAMA systematic review and meta-analysis of 74 studies across 12 countries provided further evidence of fluoride’s neurotoxicity, showing significant dose-response associations between fluoride exposure and reduced IQ in children. Even at urinary fluoride concentrations below the WHO’s 1.5 mg/L guideline ...
For every small increase of fluoride found in kids' urine, Taylor wrote, “there is a decrease of 1.63 IQ points in children.” The researchers did not suggest that fluoride should be removed ...
The debate about the benefits and risks of fluoride is ongoing, as RFK Jr. — incoming President Trump’s pick for HHS secretary — pushes to remove it from the U.S. water supply.
A U.S. government report expected to stir debate concluded that fluoride in drinking water at twice the recommended limit is linked with lower IQ in children. The report, based on an analysis of ...
In a landmark case, Fluoride Action Network and other health advocacy groups successfully argued that fluoride levels currently promoted as “optimal” by the EPA and other government agencies pose a significant threat to public health, particularly to the cognitive development of children.
Fluoride or fluorine deficiency is a disorder which may cause increased dental caries [1] and possibly osteoporosis, [2] [3] due to a lack of fluoride in diet. [4] [5] Common dietary sources of fluoride include tea, grape juice, wine, raisins, some seafood, coffee, and tap water that has been fluoridated. [6]