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This is why all modern GWAS use a very low p-value threshold. In addition to easily correctible problems such as these, some more subtle but important issues have surfaced. A high-profile GWA study that investigated individuals with very long life spans to identify SNPs associated with longevity is an example of this. [72]
In the field of genetic sequencing, genotyping by sequencing, also called GBS, is a method to discover single nucleotide polymorphisms (SNP) in order to perform genotyping studies, such as genome-wide association studies . [1] GBS uses restriction enzymes to reduce genome complexity and genotype multiple DNA samples. [2]
An important factor to consider when planning a genetic study is the frequency and risk incurred by specific alleles. These factors can vary in different populations so the HapMap project used a variety of sequencing techniques to discover and catalog SNPs from different sets of populations.
GWAS Central is a core component of the GEN2PHEN project and intends to provide an operational model, plus an open-source software package, so others can create similar databases across the world. These will be hosted by institutes, consortia, and even individual laboratories; providing those groups a toolkit for publicising and publishing ...
In 1948, Haq migrated to Pakistan. [5] In the wake of migration and the accompanying riots in 1947, much of his property, especially valuable manuscripts, papers and books were lost. [citation needed] However, some of the material which he brought to Pakistan is kept in the Urdu Dictionary Board library. [1]
An editorial in Pakistan's oldest newspaper Dawn, commenting on a report in The Guardian on Pakistani Textbooks, noted 'By propagating concepts such as jihad, the inferiority of non-Muslims, India's ingrained enmity with Pakistan, etc., the textbook board publications used by all government schools promote a mindset that is bigoted and ...
Hindi has drawn increasing focus as an academic subject. [8] There is a growing trend of Hindi experts and the availability of texts in Pakistan. [8] Many Hindi instructors migrated from India, or were educated at Indian universities. [5] The Department of Hindi at the National University of Modern Languages (NUML) in Islamabad was
Due to its importance, the Fellowships of the Pakistan Academy of Sciences are tightly restricted to the scientists who met the criteria of their qualifications. [16] Only scientists of the highest merit, who have made outstanding contributions to the advancement of scientific knowledge, are elected as Fellows of the academy.