Search results
Results From The WOW.Com Content Network
In biological research, transgenic fruit flies (Drosophila melanogaster) are model organisms used to study the effects of genetic changes on development. [122] Fruit flies are often preferred over other animals due to their short life cycle and low maintenance requirements.
Genetically modified mice are the most common animal model for transgenic research. [22] Transgenic mice are currently being used to study a variety of diseases including cancer, obesity, heart disease, arthritis, anxiety, and Parkinson's disease. [23] The two most common types of genetically modified mice are knockout mice and oncomice ...
A genetically modified mouse, genetically engineered mouse model (GEMM) [1] or transgenic mouse is a mouse (Mus musculus) that has had its genome altered through the use of genetic engineering techniques. Genetically modified mice are commonly used for research or as animal models of human diseases and are also used for research on genes.
A genetically modified organism (GMO) is any organism whose genetic material has been altered using genetic engineering techniques.The exact definition of a genetically modified organism and what constitutes genetic engineering varies, with the most common being an organism altered in a way that "does not occur naturally by mating and/or natural recombination". [1]
The first transgenic livestock were produced in 1985, [66] by micro-injecting foreign DNA into rabbit, sheep and pig eggs. [67] The first animal to synthesise transgenic proteins in their milk were mice, [68] engineered to produce human tissue plasminogen activator. [69] This technology was applied to sheep, pigs, cows and other livestock. [68]
Genetically modified mammals are mammals that have been genetically engineered.They are an important category of genetically modified organisms.The majority of research involving genetically modified mammals involves mice with attempts to produce knockout animals in other mammalian species limited by the inability to derive and stably culture embryonic stem cells.
Examples of research in which knockout mice have been useful include studying and modeling different kinds of cancer, obesity, heart disease, diabetes, arthritis, substance abuse, anxiety, aging and Parkinson's disease. Knockout mice also offer a biological and scientific context in which drugs and other therapies can be developed and tested.
Transgenic Research aims to bridge the gap between fundamental and applied science in molecular biology and biotechnology for the plant and animal academic and associated industry communities. [ 3 ] The journal is associated with the International Society for Transgenic Technologies (ISTT) .