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The NanoKnife system has also received an Investigational Device Exemption (IDE) from the FDA that allows AngioDynamics to conduct clinical trials using this device. [40] The Nanoknife system transmits a low-energy direct current from a generator to electrode probes placed in the target tissues for the surgical ablation of soft tissue.
A nanoknife is a carbon nanotube-based prototype compression cutting tool intended for sectioning of biological cells. [1] Working principle is similar to that of a 'cheese slicer' [ citation needed ] , a nanometer-thin individual carbon nanotube strung between two tungsten needles would allow sectioning of very thin slices of biological matter ...
Radiofrequency ablation (RFA), also called fulguration, [1] is a medical procedure in which part of the electrical conduction system of the heart, tumor, sensory nerves or a dysfunctional tissue is ablated using the heat generated from medium frequency alternating current (in the range of 350–500 kHz).
Pulsed field ablation (PFA) is a non-thermal (not using extreme heat or cold) method of biological ablation (removal of structure or functionality) utilizing high-amplitude pulsed (microsecond duration) electric fields to create irreversible electroporation in tissues. [1] [2] It is used most widely to treat tumors or cardiac arrhythmias. [3]
[3] [7] In February 2013, the institute introduced electrical technology as a service called 'NanoKnife', a minimally invasive cancer treatment. [8] On 12 October 2016, a new cancer center was established in NitiBagh, South Delhi by the institute.
Electro-ablation, is a process that removes material from a metallic workpiece to reduce surface roughness. Electro-ablation breaks through highly resistive oxide surfaces, such as those found on titanium and other exotic metals and alloys without melting the underlying non-oxidised metal or alloy. This allows very quick surface finishing
Various local ablation therapies exist to induce necrosis of tumor cells and release tumor antigens to stimulate an immunological response. These ablation therapies can be combined with a systemic immunotherapy: Thermal ablation – local thermal ablation of tumor: Cryoablation; Radiofrequency ablation; High-intensity focused ultrasound ablation
Microwave ablation is a form of thermal ablation used in interventional radiology to treat cancer. MWA uses electromagnetic waves in the microwave energy spectrum (300 MHz to 300 GHz) to produce tissue-heating effects.