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Mifepristone, and also known by its developmental code name RU-486, is a drug typically used in combination with misoprostol to bring about a medical abortion during pregnancy. [8] This combination is 97% effective [ 9 ] during the first 63 days (9 weeks) of pregnancy , yet effective in the second trimester as well.
The plaintiffs in the mifepristone case — anti-abortion doctors and their organizations — had argued in court papers that the Food and Drug Administration’s decisions in 2016 and 2021 to ...
The mifepristone-misoprostol combination is, by far, the most recommended drug regimen for medical abortions, but other drug combinations are available. Misoprostol alone, without mifepristone, may be used in some circumstances for medical abortion, and has even been demonstrated to be successful in the second trimester. [ 37 ]
The FDA approved mifepristone in 2000 as a safe and effective ... and an abortion procedure if the drug didn't end the pregnancy. Over the years, the FDA reaffirmed mifepristone's safety and ...
In 2000, GenBioPro's generic version of mifepristone was approved for medication abortion, as part of a two-drug regimen in combination with misoprostol. In 2023, GenBioPro sued the FDA to obtain a legal judgement confirming that mifepristone could continue to be sold, in spite of anti-abortion laws passed in some states.
The challenge to the drug had been vehemently opposed by the pharmaceutical industry, which warned that a ruling that second-guessed the regulations for mifepristone could open the door to legal ...