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Age-related cataracts are responsible for 51% of world blindness, about 20 million people. [68] Globally, cataracts cause moderate to severe disability in 53.8 million (2004), 52.2 million of whom are in low and middle income countries. [69] In many countries, surgical services are inadequate, and cataracts remain the leading cause of blindness ...
Childhood cataracts are the primary cause of childhood blindness. [4] Childhood cataracts make up 7.4% to 15.3% of blindness in kids. [4] The prevalence of childhood cataracts ranges from 0.63/10,000 to 9.74/10,000 children, with a median of 1.71. [6] This is dependent on factors like economic status but not gender or laterality. [6]
Treatment options depend on the severity of the condition. For children under the age of two years old whose vision is affected by the cataracts in both eyes, surgical options include intraocular lens implantation or a lensectomy. [2] Congenital cataracts are considered to be a significant cause of childhood blindness.
Cataracts are the leading cause of child and adult blindness that doubles in prevalence with every ten years after the age of 40. [57] Consequently, today cataracts are more common among adults than in children. [56] That is, people face higher chances of developing cataracts as they age.
Childhood blindness is an important contribution to the national prevalence of the disability of blindness. [3] Blindness in children can be defined as a visual acuity of <3/60 in the eye with better vision of a child under 16 years of age. [4]
The progression of galactosemic cataract is generally divided into three stages; initial vacuolar, late vacuolar, and nuclear cataract. The formation of a mature, nuclear, cloudy galactosemic cataract typically surfaces 14 to 15 days after the onset of the galactose diet. Fig. 6 depicts the three stages of galactosemic cataract with their ...
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[17] [16] RPE65-associated LCA is characterized by dysfunctional isomerization activity and early-onset blindness. [17] [16] RPE65. Retinoblastoma is the most common intraocular malignancy present in children younger than 5 years old. The eye cancer can be passed down genetically as an autosomal dominant condition. [18] [19]