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  2. Adrenergic receptor - Wikipedia

    en.wikipedia.org/wiki/Adrenergic_receptor

    Epinephrine (adrenaline) reacts with both α- and β-adrenoreceptors, causing vasoconstriction and vasodilation, respectively. Although α receptors are less sensitive to epinephrine, when activated at pharmacologic doses, they override the vasodilation mediated by β-adrenoreceptors because there are more peripheral α 1 receptors than β ...

  3. Adrenaline - Wikipedia

    en.wikipedia.org/wiki/Adrenaline

    Adrenaline, also known as epinephrine, is a hormone and medication [10] [11] which is involved in regulating visceral functions (e.g., respiration). [10] [12] It appears as a white microcrystalline granule. [13] Adrenaline is normally produced by the adrenal glands and by a small number of neurons in the medulla oblongata. [14]

  4. Beta-2 adrenergic receptor - Wikipedia

    en.wikipedia.org/wiki/Beta-2_adrenergic_receptor

    The beta-2 adrenergic receptor (β 2 adrenoreceptor), also known as ADRB2, is a cell membrane-spanning beta-adrenergic receptor that binds epinephrine (adrenaline), a hormone and neurotransmitter whose signaling, via adenylate cyclase stimulation through trimeric G s proteins, increases cAMP, and, via downstream L-type calcium channel interaction, mediates physiologic responses such as smooth ...

  5. Epinephrine (medication) - Wikipedia

    en.wikipedia.org/wiki/Epinephrine_(medication)

    Epinephrine, also known as adrenaline, is a medication and hormone. [10] [11] As a medication, it is used to treat several conditions, including anaphylaxis, cardiac arrest, asthma, and superficial bleeding. [8] Inhaled epinephrine may be used to improve the symptoms of croup. [12] It may also be used for asthma when other treatments are not ...

  6. Sympathoadrenal system - Wikipedia

    en.wikipedia.org/wiki/Sympathoadrenal_system

    The right kidney depicted has a tumor (shown inside the red circle). This disease is called pheochromocytoma and causes an increased level of adrenaline to be released into the circulatory system. Hypoglycemia, or low blood glucose, causes cardiovascular physiological effects as a result of the sympathoadrenal system. These physiological ...

  7. Sympathetic nervous system - Wikipedia

    en.wikipedia.org/wiki/Sympathetic_nervous_system

    Sympathetic nervous system stimulation causes vasoconstriction of most blood vessels, including many of those in the skin, the digestive tract, and the kidneys. This occurs due to the activation of alpha-1 adrenergic receptors by norepinephrine released by post-ganglionic sympathetic neurons.

  8. Discovery and development of beta2 agonists - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    COPD causes airflow limitations in the lungs because of inflammation. Smoking is the main risk factor but inhalation of toxic and harmful particles and gases can also cause the disease. The symptoms are abnormal mucus production, inflation in the lungs that causes airflow limitation, abnormal gas exchange and pulmonary hypertension.

  9. Hypovolemia - Wikipedia

    en.wikipedia.org/wiki/Hypovolemia

    This sympathetic response is to release epinephrine and norepinephrine, which results in peripheral vasoconstriction (reducing size of blood vessels) in order to conserve the circulating fluids for organs vital to survival (i.e. brain and heart). Peripheral vasoconstriction accounts for the cold extremities (hands and feet), increased heart ...