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Epidemiological (and other observational) studies typically highlight associations between exposures and outcomes, rather than causation. While some consider this a limitation of observational research, epidemiological models of causation (e.g. Bradford Hill criteria) [7] contend that an entire body of evidence is needed before determining if an association is truly causal. [8]
Patient recruitment is the process of finding and enrolling suitable participants for clinical trials. It is a crucial aspect of drug development and medical research, as it affects the validity, reliability, and generalizability of the results.
National Cancer Institute video on clinical trial phases. The phases of clinical research are the stages in which scientists conduct experiments with a health intervention to obtain sufficient evidence for a process considered effective as a medical treatment. [1]
The Most Significant Change Technique (MSC) is a monitoring and evaluation (M&E) method used for the monitoring and evaluating of complex development interventions. It was developed by Rick Davies as part of his PhD field work with the Christian Commission for Development in Bangladesh (CCDB) in 1994. [1]
A standard operating procedure (SOP) is a set of step-by-step instructions compiled by an organization to help workers carry out routine operations. [1] SOPs aim to achieve efficiency, quality output, and uniformity of performance, while reducing miscommunication and failure to comply with industry regulations.
Prostanoid research, pharmacological inhibition of COXs versus the microsomal PGE synthase– 1, [74] involved in the interdisciplinary PENTACON consortium, integration of basic and clinical research in yeast, mammalian cells, fish, mice and humans with the objective of predicting NSAID efficacy and cardiovascular hazard in patients
In the standard preregistration format, researchers prepare a research protocol document prior to conducting their research. Ideally, this document indicates the research hypotheses, sampling procedure, sample size, research design, testing conditions, stimuli, measures, data coding and aggregation method, criteria for data exclusions, and statistical analyses, including potential variations ...
The process could be modified through a change in standard protocol of determining how and when an alert is released and who is responsible for each step in the process. The outcomes to evaluate the efficacy of this quality improvement (QI) solution might include patient satisfaction, timeliness of diagnosis, or clinical outcomes.