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  2. Chronic myelogenous leukemia - Wikipedia

    en.wikipedia.org/wiki/Chronic_myelogenous_leukemia

    Chronic myelogenous leukemia (CML), also known as chronic myeloid leukemia, is a cancer of the white blood cells. It is a form of leukemia characterized by the increased and unregulated growth of myeloid cells in the bone marrow and the accumulation of these cells in the blood.

  3. Bcr-Abl tyrosine-kinase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Bcr-Abl_tyrosine-kinase...

    Bcr-Abl tyrosine-kinase inhibitors (TKI) are the first-line therapy for most patients with chronic myelogenous leukemia (CML). More than 90% of CML cases are caused by a chromosomal abnormality that results in the formation of a so-called Philadelphia chromosome.

  4. Accelerated phase chronic myelogenous leukemia - Wikipedia

    en.wikipedia.org/wiki/Accelerated_phase_chronic...

    2 Treatment. 3 Prognosis. 4 References. ... Accelerated phase chronic myelogenous leukemia is a phase of chronic myelogenous leukemia in which the disease is ...

  5. Cytarabine - Wikipedia

    en.wikipedia.org/wiki/Cytarabine

    Cytarabine, also known as cytosine arabinoside (ara-C), is a chemotherapy medication used to treat acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), chronic myelogenous leukemia (CML), and non-Hodgkin's lymphoma. [2] It is given by injection into a vein, under the skin, or into the cerebrospinal fluid. [2]

  6. Bosutinib - Wikipedia

    en.wikipedia.org/wiki/Bosutinib

    Bosutinib received US FDA and EU European Medicines Agency approval in September 2012, and March 2013, respectively for the treatment of adults with Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML) with resistance, or intolerance to prior therapy. [6] [7] [8] [9]

  7. Imatinib - Wikipedia

    en.wikipedia.org/wiki/Imatinib

    It is also used to maintain remission in chronic phase CML patients. While Imatinib is a very effective treatment for CML and some types of ALL, it is not a cure for leukemia. Instead, it is a 'chronic therapy' that helps to control the disease and prevent it from progressing.

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