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Chemotherapy-induced nausea and vomiting (CINV) is a common side-effect of many cancer treatments. Nausea and vomiting are two of the most feared cancer treatment-related side effects for cancer patients and their families.
Anticipatory nausea and vomiting is experienced by approximately 20–30% of people undergoing chemotherapy. [20] Chemotherapy-induced nausea and vomiting resulting from treatment with highly emetogenic cytotoxic drugs can be prevented or effectively treated in 70 to 80% of affected people. [4] [16]
The neurotransmitters implicated in the control of nausea and vomiting include acetylcholine, dopamine, histamine (H1 receptor), substance P (NK-1 receptor), and serotonin (5-HT3 receptor). There are also opioid receptors present, which may be involved in the mechanism by which opiates cause nausea and vomiting.
“An empty stomach can definitely worsen nausea,” says ... in some studies to help alleviate nausea and vomiting," Upton says. ... morning sickness and for chemotherapy-induced nausea." For ...
The discovery of neurokinin 1 (NK 1) receptor antagonists was a turning point in the prevention of nausea and vomiting associated with cancer chemotherapy. [4] An example of a drug in this class is aprepitant. Chemotherapy-induced emesis appears to consist of acute and delayed phases.
Nausea. Vomiting. Diarrhea. Stomach cramps. Headache. Fever. Body aches. People with norovirus usually get better within one to three days, according to the CDC. ... 24-hour flu treatment.
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