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  2. Colon cancer staging - Wikipedia

    en.wikipedia.org/wiki/Colon_cancer_staging

    The T stages of bowel cancer. Numbers 0 to 4, with subgroups, are used to describe deepest tumor depth: [2] TX: The primary tumor cannot be evaluated. T0: No evidence of cancer in the colon or rectum. Tis: Carcinoma in situ; Cancer cells are found only in the epithelium or lamina propria; T1: Growth into the submucosa; T2: Growth into the ...

  3. Timeline of cancer treatment development - Wikipedia

    en.wikipedia.org/wiki/Timeline_of_cancer...

    1900 – Swedish Dr. Stenbeck cures a skin cancer with small doses of radiation [4]; 1920s – Dr. William B. Coley's immunotherapy treatment, regressed tumors in hundreds of cases, the success of Coley's Toxins attracted heavy resistance from his rival and supervisor, Dr. James Ewing, who was an ardent supporter of radiation therapy for cancer.

  4. Colorectal cancer - Wikipedia

    en.wikipedia.org/wiki/Colorectal_cancer

    Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine). [5] Signs and symptoms may include blood in the stool , a change in bowel movements , weight loss, abdominal pain and fatigue. [ 9 ]

  5. Tumor progression - Wikipedia

    en.wikipedia.org/wiki/Tumor_progression

    MRI scans of a patient with astrocytoma, showing the tumor's progression between the incidental finding in 2007 and the onset of phenotypical changes in 2014. Tumor progression is the third and last phase in tumor development. [1] This phase is characterised by increased growth speed and invasiveness of the tumor cells.

  6. Tumor promotion - Wikipedia

    en.wikipedia.org/wiki/Tumor_promotion

    Tumor promotion is a process in carcinogenesis by which various factors permit the descendants of a single initiated cell to survive and expand in number, i.e. to resist apoptosis and to undergo clonal growth. [1] This is a step toward tumor progression. [2] [3]

  7. Malignant transformation - Wikipedia

    en.wikipedia.org/wiki/Malignant_transformation

    Colon cancer provides one example of the mechanisms by which diet, the top factor listed in the table, is an external factor in cancer. The Western diet of African Americans in the United States is associated with a yearly colon cancer rate of 65 per 100,000 individuals, while the high fiber/low fat diet of rural Native Africans in South Africa is associated with a yearly colon cancer rate of ...

  8. Mouse model of colorectal and intestinal cancer - Wikipedia

    en.wikipedia.org/wiki/Mouse_model_of_colorectal...

    Furthermore, when evaluated for ERCC1, beclin-1, and beta-catenin in the stem cell region of crypts, the colonic tissues of chlorogenic acid-fed mice showed amelioration of the molecular aberrancies, [29] suggesting that chlorogenic acid is protective at the molecular level against colon cancer. This is the first diet-related model of colon ...

  9. Response evaluation criteria in solid tumors - Wikipedia

    en.wikipedia.org/wiki/Response_Evaluation...

    These new criteria have been widely adopted and embraced by the regulatory authorities. [1] The mean response rate for new cancer drugs approved by the U.S. Food and Drug Administration, expressed as relative risk, ranges between 1.38x [3] and 2.37x. [4]