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By extension, the derivatives are also referred to as oxazines; examples include ifosfamide and morpholine (tetrahydro-1,4-oxazine). A commercially available dihydro-1,3-oxazine is a reagent in the Meyers synthesis of aldehydes. Fluorescent dyes such as Nile red and Nile blue are based on the aromatic compound benzophenoxazine. Cinnabarine and ...
Polybenzoxazines, also called benzoxazine resins, are a class of polymers that are produced from the ring-opening polymerization of 3-phenyl-2,4-dihydro-1,3-benzoxazine monomers and its chemical derivatives. [6] The main applications of polybenzoxazines are as adhesives and in fiber-reinforced plastics.
Benzoxazines are bicyclic heterocyclic compounds containing one oxygen and one nitrogen atom in a doubly unsaturated six-member ring, specifically a 1,3-oxazine ring, fused with a benzene ring. The systematic IUPAC name of the prototypical unsubstituted monomer is 3,4-dihydro-3-phenyl-2 H -1,3-benzoxazine.
The starting compound is a dihydro-1,3-oxazine with an alkyl group in the 2 position. The alpha proton is acidic and can be abstracted by a strong base such as butyl lithium and subsequently alkylated by an alkyl halide ( haloalkane ).
Viloxazine is indicated to treat attention deficit hyperactivity disorder (ADHD) in children age 6 to 12 years, adolescents age 13 to 17 years, and adults. [1]Analyses of clinical trial data suggest that viloxazine produces moderate reductions in symptoms; it is about as effective as atomoxetine and methylphenidate but with fewer side effects.
G-130 (GP-130, 2-Phenyl-5,5-dimethyltetrahydro-1,4-oxazine) [1] is a drug with stimulant and anorectic effects, related to phenmetrazine. [2] [3] [4] Structural analogs
It has a centrosymmetric angular structure. [2] For many years, the structure was assigned, incorrectly, as having a "linear structure" (EC no. 228-767-9, CAS RN 6358-30-1) which differ in terms of the carbazole ring fusion. [3] Pigment violet 23 is prepared by condensation of an aniline with chloranil. [4]
Brilaroxazine acts as a potent partial agonist of D 2, D 3, D 4 and 5-HT 1A receptors, and as an antagonist of 5-HT 2A, 5-HT 2B, 5-HT 2C, 5-HT 6 and 5-HT 7 receptors. [9] [11] Brilaroxazine exhibits high affinity for D 2S, D 2L, D 3, D 4.4, 5-HT 1A, 5-HT 2A, 5-HT 2B, and 5-HT 7 receptors, and moderate affinity for D 1, D 5, 5-HT 2C, 5-HT 3, 5-HT 6, H 1 and α 4 β 2 nicotinic receptors, the ...