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The prevalence of this condition stands at about 24 to 30 cases per 100,000 people while 0.7 to 3.0 new cases per 100,000 people are reported every year. Delusional disorder accounts for 1–2% of admissions to inpatient mental health facilities. [7] [30] The incidence of first admissions for delusional disorder is lower, from 0.001 to 0.003%. [31]
This condition is often seen in disorders like schizophrenia, schizoaffective disorder, delusional disorder, manic episodes of bipolar disorder, psychotic depression, and some personality disorders. [2] [3] Alongside delusional jealousy, persecutory delusion is the most common type of delusion in males and is a frequent symptom of psychosis.
Typically, treatment of delusional disorders is challenging due to poor patient insight and lack of empirical data. [41] Treatment is generally therapy, often with support of antipsychotic medication. [45] [46] [47] As manifestation of Capgras delusion is often a symptom rather than a syndrome itself, treatment may focus on the accompanying ...
Treatment for this disorder gains the best results when tailored specifically for each individual. To date, the mainline pharmacological treatments have been pimozide (a typical antipsychotic which was also approved for treating Tourette's syndrome), [4] [5] and atypical antipsychotics like risperidone and clozapine.
While non-delusional grandiose beliefs are somewhat common—occurring in at least 10% of the general population [3] —and often [vague] positively influence a person's self-esteem, in some cases they may cause a person distress, in which case such beliefs may be clinically evaluated and diagnosed as a psychiatric disorder.
Paraphrenia is often associated with a physical change in the brain, such as a tumor, stroke, ventricular enlargement, or neurodegenerative process. [4] Research that reviewed the relationship between organic brain lesions and the development of delusions suggested that "brain lesions which lead to subcortical dysfunction could produce delusions when elaborated by an intact cortex".