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It typically costs more than generic finasteride — a month’s supply of Propecia usually costs $100 to $150, depending on your pharmacy or healthcare provider of choice.
Side Effects of Finasteride 5mg. Compared to the 1mg dose, finasteride 5mg has a few more noticeable side effects. In clinical trials, eight percent of men on finasteride 5mg experienced ED, six ...
[71] [72] An oral dosage of finasteride of only 0.2 mg/day has been found to achieve near-maximal suppression of DHT levels (68.6% for 0.2 mg/day relative to 72.2% for 5 mg/day). [72] [73] Finasteride does not completely suppress DHT production because it lacks significant inhibitory effects on the 5α-reductase type I isoenzyme, with more than ...
As a treatment for benign prostatic hyperplasia (BPH), finasteride is used at a dosage of 5 mg per day. This dose can be found in generic forms of finasteride and the brand-name medication Proscar.
There were no differences in the rates of depression, self-harm, and suicide between finasteride and dutasteride, suggesting that the specific 5-ARI used does not influence the risks. [ 33 ] [ 21 ] [ 34 ] The absolute risks of self-harm and depression with 5-ARIs remain low (0.14% and 2.0%, respectively).
Structure of finasteride. Finasteride mainly inhibits the 5α-R2 (IC50=69 nM) and 5α-R3 (IC50=17.4 nM) with little inhibition of 5α-R1 (IC50=360 nM). As mentioned above, finasteride reduces prostatic DHT levels on a 70-90% range but the detailed reduction of DHT is 70.8% and 85% of intraprostatic DHT. [6]