Search results
Results From The WOW.Com Content Network
Disulfiram-alcohol reaction (DAR) is the effect of the interaction in the human body of alcohol drunk with disulfiram or some types of mushrooms. [ 1 ] [ 2 ] The DAR is key to disulfiram therapy that is widely used for alcohol-aversive treatment and management of other addictions (e.g. cocaine [ 3 ] [ 4 ] use).
A disulfiram-like drug is a drug that causes an adverse reaction to alcohol leading to nausea, vomiting, flushing, dizziness, throbbing headache, chest and abdominal discomfort, and general hangover-like symptoms among others.
Disulfiram is a medication used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol (drinking alcohol). Disulfiram works by inhibiting the enzyme aldehyde dehydrogenase (specifically the ALDH2 enzyme [3]), causing many of the effects of a hangover to be felt immediately following alcohol consumption.
No description. Template parameters [Edit template data] Parameter Description Type Status 1 1 no description Unknown optional The above documentation is transcluded from Template:DrugBank/doc. (edit | history) Editors can experiment in this template's sandbox (create | mirror) and testcases (create) pages. Add categories to the /doc subpage. Subpages of this template.
This template is used on approximately 14,000 pages and changes may be widely noticed. Test changes in the template's /sandbox or /testcases subpages, or in your own user subpage . Consider discussing changes on the talk page before implementing them.
The tetramethyl derivative, known as thiram, is a widely used fungicide.The tetraethyl derivative, known as disulfiram, is commonly used to treat chronic alcoholism.It produces an acute sensitivity to alcohol ingestion by blocking metabolism of acetaldehyde by acetaldehyde dehydrogenase, leading to a higher concentration of the aldehyde in the blood, which in turn produces symptoms of a severe ...
Disulfiram has been proposed as another proteasome inhibitor. [10] [11] [12] Epigallocatechin-3-gallate has also been proposed. [13] Marizomib (salinosporamide A) has started clinical trials for multiple myeloma. Oprozomib (ONX-0912), delanzomib (CEP-18770) have also started clinical trials. [14] Epoxomicin is a naturally occurring selective ...
Main page; Contents; Current events; Random article; About Wikipedia; Contact us; Donate