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The incidence of hypoglycemia due to complex drug interactions, especially involving oral hypoglycemic agents and insulin for diabetes, rises with age. Though much rarer, the incidence of insulin-producing tumors also rises with advancing age. Most tumors causing hypoglycemia by mechanisms other than insulin excess occur in adults. [citation ...
Inborn errors of metabolism may cause infant hypoglycemia, and much less commonly adult hypoglycemia. [25] Disorders that are related to the breakdown of glycogen, called glycogen storage diseases, may cause hypoglycemia. [3] [25] Normally, breakdown of glycogen leads to increased glucose levels, particularly in a fasting state. [3]
Specific manifestations vary by age and by the severity of the hypoglycemia. In older children and adults, moderately severe hypoglycemia can resemble mania, mental illness, drug intoxication, or drunkenness. In the elderly, hypoglycemia can produce focal stroke-like effects or a hard-to-define malaise.
The most common cause of hypoglycemia is medications used to treat diabetes mellitus such as insulin and sulfonylureas. [ 9 ] [ 10 ] Risk is greater in diabetics who have eaten less than usual, exercised more than usual or have drunk alcohol . [ 8 ]
Manifestations of hyperinsulinemic hypoglycemia vary by age and severity of the hypoglycemia. In general, most signs and symptoms can be attributed to (1) the effects on the brain of insufficient glucose (neuroglycopenia) or (2) to the adrenergic response of the autonomic nervous system to hypoglycemia. A few miscellaneous symptoms are harder ...
Being 45 or older. Health conditions like high blood pressure, high cholesterol, metabolic syndrome, or sleep apnea. Having a medical history of gestational diabetes, heart disease, or stroke.