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During oxygen deprivation, cells die due to an increasing acidity in the brain tissue . Additionally, during the period of oxygen deprivation, materials that can easily create free radicals build up. When oxygen enters the tissue these materials interact with oxygen to create high levels of oxidants.
This leads to poor oxygen supply or cerebral hypoxia and thus leads to the death of brain tissue or cerebral infarction/ischemic stroke. [2] It is a sub-type of stroke along with subarachnoid hemorrhage and intracerebral hemorrhage. [3] Ischemia leads to alterations in brain metabolism, reduction in metabolic rates, and energy crisis. [4]
Tissue hypoxia from low oxygen delivery may be due to low haemoglobin concentration (anaemic hypoxia), low cardiac output (stagnant hypoxia) or low haemoglobin saturation (hypoxic hypoxia). [79] The consequence of oxygen deprivation in tissues is a switch to anaerobic metabolism at the cellular level.
A stroke is like the brain’s version of a heart attack — and is also life-threatening. When the blood flow to the heart is blocked, we call it a heart attack. And when blood flow to the brain ...
The main reason for the acute phase of ischemia-reperfusion injury is oxygen deprivation and, therefore, arrest of generation of ATP (cellular energy currency) by mitochondria oxidative phosphorylation. Tissue damage due to the general energy deficit during ischemia is followed by reperfusion (increase of oxygen level) when the injury is enhanced.
When Chris Kirmsee had COVID-19, her oxygen levels dropped low enough that Christine Kirmsee sent her to the emergency room. It was a good thing because Chris Kirmsse had developed pneumonia and ...
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