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Histopathological image of dyshidrotic dermatitis, showing focal spongiotic change in the epidermis. Spongiosis is mainly intercellular [1] edema (abnormal accumulation of fluid) in the epidermis, [2] and is characteristic of eczematous dermatitis, manifested clinically by intraepidermal vesicles (fluid-containing spaces), "juicy" papules, and/or lichenification. [3]
IV. Spongiotic dermatitis: Presence of more than 10 tadpole cells at x100 magnification Contact dermatitis: Tadpole cells and lymphocytes 83% sensitive and 100% specific V. Granulomatous diseases: Granuloma formation and multinucleated giant cells The main purpose of cytological examination in granulomatous dermatitis is to detect infectious ...
The spongiosis is mild to absent; Pronounced irregular acanthosis, hyperkeratosis, and parakeratosis; Minimal dermal inflammation and exocytosis of inflammatory cells are present. Possibly fibrosis of papillary dermis; PAS stain is essential to exclude fungal infection. [2] Subacute Allergic/contact dermatitis or atopic dermatitis As above.
Patch testing may be considered if there is suspicion of allergic contact dermatitis. [2] A skin biopsy is rarely necessary, [2] but if done mostly shows an interstitial granulomatous dermatitis, some lesions being spongiotic. [4] Id reactions cannot be distinguished from other skin diseases by histopathology.
Dermatitis was estimated to affect 245 million people globally in 2015, [6] or 3.34% of the world population. Atopic dermatitis is the most common type and generally starts in childhood. [1] [2] In the United States, it affects about 10–30% of people. [2] Contact dermatitis is twice as common in females as in males. [11]
A non-specific histologic examination reveals superficial spongiotic dermatitis connected to a hair follicle and the surrounding epidermis. A mention of exocytosis is made in the spongiotic region. Inflammatory cells are present in the subadjacent dermis, while the deeper dermis is unaffected. [2]
Eczema refers to a broad range of conditions that begin as spongiotic dermatitis and may progress to a lichenified stage. Pages in category "Eczema" The following 44 pages are in this category, out of 44 total.
Micrograph of Schamberg disease, suggesting the spongiotic stage of a purpuric dermatitis. Additional testing may aid diagnosis. A skin biopsy may be taken to determine capillaritis of dermal vessels. [8] Capillaritis or pigmented purpura is skin condition that has brown-reddish patches on the skin, which is caused by leaky capillaries. [9]
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