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The log diagnostic odds ratio can also be used to study the trade-off between sensitivity and specificity [5] [6] by expressing the log diagnostic odds ratio in terms of the logit of the true positive rate (sensitivity) and false positive rate (1 − specificity), and by additionally constructing a measure, :
The calculation of likelihood ratios for tests with continuous values or more than two outcomes is similar to the calculation for dichotomous outcomes; a separate likelihood ratio is simply calculated for every level of test result and is called interval or stratum specific likelihood ratios. [6] The pretest odds of a particular diagnosis ...
The positive predictive value (PPV), or precision, is defined as = + = where a "true positive" is the event that the test makes a positive prediction, and the subject has a positive result under the gold standard, and a "false positive" is the event that the test makes a positive prediction, and the subject has a negative result under the gold standard.
An odds ratio greater than 1 indicates that the condition or event is more likely to occur in the first group. And an odds ratio less than 1 indicates that the condition or event is less likely to occur in the first group. The odds ratio must be nonnegative if it is defined. It is undefined if p 2 q 1 equals zero, i.e., if p 2 equals zero or q ...
This is primarily done for the column (condition) ratios, yielding likelihood ratios in diagnostic testing. Taking the ratio of one of these groups of ratios yields a final ratio, the diagnostic odds ratio (DOR). This can also be defined directly as (TP×TN)/(FP×FN) = (TP/FN)/(FP/TN); this has a useful interpretation – as an odds ratio ...
Diagnostic odds ratio; G-test; Generalized estimating equations; Generalized linear models; Krichevsky–Trofimov estimator; Kuder–Richardson Formula 20; Linear discriminant analysis; Multinomial distribution; Multinomial logit; Multinomial probit; Multiple correspondence analysis; Odds ratio; Poisson regression; Powered partial least squares ...
and = / / = While the prevalence is only 9% (9/100), the odds ratio (OR) is equal to 11.3 and the relative risk (RR) is equal to 7.2. Despite fulfilling the rare disease assumption overall, the OR and RR can hardly be considered to be approximately the same. However, the prevalence in the exposed group is 40%, which means is not sufficiently small
McNemar's test is a statistical test used on paired nominal data.It is applied to 2 × 2 contingency tables with a dichotomous trait, with matched pairs of subjects, to determine whether the row and column marginal frequencies are equal (that is, whether there is "marginal homogeneity").