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Naltrexone/bupropion, sold under the brand name Contrave among others, is a fixed-dose combination medication for the management of chronic obesity in adults in combination with a reduced-calorie diet and increased physical activity. [4] [6] It contains naltrexone, an opioid antagonist, and bupropion, an aminoketone atypical antidepressant. [4]
Only 13% of patients who started taking Contrave from Orexigen Therapeutics and 10% of those who started on Qsymia from Vivus between 2015 and 2022 were still filling their prescriptions a year ...
Qsymia Phentermine is a substituted amphetamine and topiramate has an unknown mechanism of action Approved for weight management (short-term) by the FDA but not the European Medicines Agency [54] 10% [55] or 8.25 kilograms (18.2 lb) [56] Naltrexone/bupropion: Contrave Approved for weight management (chronic) in the US and EU [57] 5 percent [17 ...
Sold under the brand name Qsymia, it is a combination of the drugs phentermine and topiramate, which are taken orally. The medications are used, along with changes in diet and exercise habits, to ...
[8] [14] Naltrexone, as naltrexone/bupropion (brand name Contrave), is also used to treat obesity. [15] It is on the World Health Organization's List of Essential Medicines. [16] In 2021, it was the 254th most commonly prescribed medication in the United States, with more than 1 million prescriptions. [17] [18]
Contrave. Contrave is yet another oral weight loss medication. ... Like many Ozempic alternatives, Qsymia is FDA-approved for weight management in people with a BMI of 30 or more, or 27 or more ...
In clinical trials, the most common adverse events which occurred at a rate ≥5% and ≥1.5 times placebo included paraesthesia (tingling in fingers/toes), dizziness, altered taste, insomnia, constipation, and dry mouth.
Contrave® (naltrexone-bupropion) Topamax® Xenical® (orlistat) Qsymia® (phentermine-topiramate) And there are lifestyle changes you can make to lose weight, such as: Eating nutritious foods. ...