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Encephalitis lethargica is an atypical form of encephalitis.Also known as "sleeping sickness" or "sleepy sickness" (distinct from tsetse fly–transmitted sleeping sickness), it was first described in 1917 by neurologist Constantin von Economo [2] [3] and pathologist Jean-René Cruchet. [4]
Encephalitis with meningitis is known as meningoencephalitis, while encephalitis with involvement of the spinal cord is known as encephalomyelitis. [ 2 ] The word is from Ancient Greek ἐγκέφαλος , enképhalos 'brain', [ 37 ] composed of ἐν , en , 'in' and κεφαλή , kephalé , 'head', and the medical suffix -itis 'inflammation'.
Historically, starting in 1917 an epidemic of encephalitis lethargica, also called von Economo's encephalitis or "sleepy-disease" occurred, possibly related to the 1918 Spanish flu pandemic; however, even with the use of modern molecular diagnostic tests on appropriate corpses, no firm link between encephalitis lethargica and influenza has been ...
Encephalitis lethargica is a neurological syndrome that causes lethargy, a “mask like” face, excessive blood in the meninges, and other general neurological symptoms. [5] Officially recognized as its own condition in 1917, it is believed to have existed far longer in human history. [ 5 ]
A human case of Eastern equine encephalitis was identified in Massachusetts for the first time since 2020. Now the state's public health department is ringing the alarm in multiple communities to ...
If hypoxia results in coma, the length of unconsciousness is often indicative of long-term damage. In some cases coma can give the brain an opportunity to heal and regenerate, [ 34 ] but, in general, the longer a coma, the greater the likelihood that the person will remain in a vegetative state until death. [ 9 ]
Overview of signal transduction pathways involved in apoptosis. Cell death is the event of a biological cell ceasing to carry out its functions. This may be the result of the natural process of old cells dying and being replaced by new ones, as in programmed cell death, or may result from factors such as diseases, localized injury, or the death of the organism of which the cells are part.
Postvaccinal encephalitis (PVE) is a rare complication which was associated with vaccination with vaccinia virus during the worldwide smallpox eradication campaign. [1] With mortality ranging between 25 – 30% it is the most severe adverse event associated with this vaccination. The mechanism of how it happens is unknown. [2]
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