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  2. Elevated alkaline phosphatase - Wikipedia

    en.wikipedia.org/wiki/Elevated_alkaline_phosphatase

    Elevated alkaline phosphatase in patients with cancer normally spans [clarification needed] throughout the bones or liver. Metastases that exist in the lung, breast, prostate, colon, thyroid, and further organs can also enter the liver or bone. [ 12 ]

  3. Alkaline phosphatase - Wikipedia

    en.wikipedia.org/wiki/Alkaline_phosphatase

    The enzyme alkaline phosphatase (ALP, alkaline phenyl phosphatase) is a phosphatase with the physiological role of dephosphorylating compounds. The enzyme is found across a multitude of organisms, prokaryotes and eukaryotes alike, with the same general function, but in different structural forms suitable to the environment they function in. Alkaline phosphatase is found in the periplasmic ...

  4. Liver function tests - Wikipedia

    en.wikipedia.org/wiki/Liver_function_tests

    Standard liver tests for assessing liver damage include alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP). Bilirubin may be used to estimate the excretory function of the liver and coagulation tests and albumin can be used to evaluate the metabolic activity of the liver. [6]

  5. Acute liver failure - Wikipedia

    en.wikipedia.org/wiki/Acute_liver_failure

    Acute liver failure is the appearance of severe complications rapidly ... signs of elevated intracranial ... AST, ALT, alkaline phosphatase, GGT, total ...

  6. Hepatotoxicity - Wikipedia

    en.wikipedia.org/wiki/Hepatotoxicity

    Biochemical markers (e.g. alanine transferase, alkaline phosphatase and bilirubin) are often used to indicate liver damage. Liver injury is defined as a rise in either (a) ALT level more than three times of upper limit of normal (ULN), (b) ALP level more than twice ULN, or (c) total bilirubin level more than twice ULN when associated with ...

  7. Primary biliary cholangitis - Wikipedia

    en.wikipedia.org/wiki/Primary_biliary_cholangitis

    Abnormalities in liver enzyme tests are usually present and elevated gamma-glutamyl transferase and alkaline phosphatase are found in early disease. [11] Elevations in bilirubin occur in advanced disease. Antimitochondrial antibodies are the characteristic serological marker for PBC, being found in 90–95% of patients and only 1% of controls.

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