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Aspirin is an effective analgesic for acute pain, although it is generally considered inferior to ibuprofen because aspirin is more likely to cause gastrointestinal bleeding. [91] Aspirin is generally ineffective for those pains caused by muscle cramps , bloating , gastric distension , or acute skin irritation. [ 92 ]
Acetylsalicylic acid (Aspirin) - An extremely common NSAID that has anticoagulant effects Dipyridamole , a drug that inhibits platelet activation [ 2 ] when given chronically and causes vasodilation when given at high doses over short time.
Janet O'Mahony, a Baltimore-area internal medicine doctor at Mercy Medical Center, tells Yahoo Life: “Where aspirin is used more commonly these days is as an antiplatelet agent,” or blood ...
Antiplatelet therapy with one or more of these drugs decreases the ability of blood clots to form by interfering with the platelet activation process in primary hemostasis. Antiplatelet drugs can reversibly or irreversibly inhibit the process involved in platelet activation resulting in decreased tendency of platelets to adhere to one another ...
The second generation thienopyridine P2Y 12 receptor blocker clopidogrel is an effective antiplatelet agent useful for treatment of ischemic cerebrovascular, cardiac and peripheral arterial release. [27] Like other thienopyridine drugs, the drug was often combined with aspirin in clinical use. [23]
An antithrombotic agent is a drug that reduces the formation of blood clots (). [1] [2] Antithrombotics can be used therapeutically for prevention (primary prevention, secondary prevention) or treatment of a dangerous blood clot (acute thrombus).
Aside from aspirin, three antiplatelet agents taken by mouth have been approved for use in acute coronary syndromes, clopidogrel, ticagrelor and prasugrel; all reduce platelet aggregation by inhibiting the P2Y 12 receptor, a type of adenosine phosphate receptor, on the surface of platelets. Not all three of them are equally indicated in all ...
In the 2008, guidelines for stroke management from the European Stroke Organization, [3] triflusal was for the first time recommended as lone therapy, as an alternative to acetylsalicylic acid (ASA)(Aspirin) plus dipyridamole, or clopidogrel alone for secondary prevention of atherothrombotic stroke.