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rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, psoriasis, Crohn's disease, ulcerative colitis Intetumumab [83] [84] mab: human: CD51: solid tumors (prostate cancer, melanoma) Inolimomab: mab: mouse: CD25 (α chain of IL-2 receptor) graft versus host disease: Inotuzumab ozogamicin [39] Besponsa: mab: humanized: CD22: Y: Acute ...
As a result, this type of biologic inhibits T cell proliferation and B cell immunological response. [20] Abatacept is available as an antiarthritic medication for moderate to severe RA. This biologic can also be used to treat patients with juvenile rheumatoid arthritis. [14] Examples: [16] Abatacept
Rheumatoid arthritis Ankylosing spondylitis Psoriatic arthritis Plaque psoriasis: 125544: Link: infliximab-qbtx: Ixifi: Pfizer: 12/13/17: intravenous: chimeric, biosimilar: TNF: Crohn's disease Ulcerative colitis Rheumatoid arthritis Ankylosing spondylitis Psoriatic arthritis Plaque psoriasis: 761072: Link: inotuzumab ozogamicin: Besponsa ...
For people with moderate to severe psoriatic arthritis, biologics can provide some relief of the symptoms, [4] and even slow down or halt the progression of the disease. Classes of biologics typically used for psoriatic arthritis include TNF inhibitors, anti-IL17-A antibodies, IL-23 antibodies, and those that act on both IL-12 and IL-23. [7]
Sulfasalazine also appears to be most effective in the short-term treatment of rheumatoid arthritis. [121] Hydroxychloroquine, in addition to its low toxicity profile, is considered effective for treatment of moderate RA symptoms. [122] Agents may be used in combination, however, people may experience greater side effects.
Although the use of the term DMARDs was first propagated in rheumatoid arthritis (hence their name), the term has come to pertain to many other diseases, such as Crohn's disease, lupus erythematosus, Sjögren syndrome, immune thrombocytopenic purpura, myasthenia gravis, sarcoidosis, and various others. [citation needed]
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