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Meningococcal_meningitis_A,C,Y,W-135_Vaccine.png (226 × 536 pixels, file size: 191 KB, MIME type: image/png) This is a file from the Wikimedia Commons . Information from its description page there is shown below.
Kernig's sign is a test used in physical examination to look for evidence of irritation of the meninges. The test involves flexing the thighs at the hip, and the knees, at 90 degree angles, and assessing whether subsequent extension of the knee is painful (leading to resistance), in which case it is deemed positive. [ 1 ]
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Eponymous medical signs are those that are named after a person or persons, usually the physicians who first described them, but occasionally named after a famous patient. This list includes other eponymous entities of diagnostic significance; i.e. tests, reflexes, etc.
Meningococcal vaccine refers to any vaccine used to prevent infection by Neisseria meningitidis. [9] Different versions are effective against some or all of the following types of meningococcus: A, B, C, W-135, and Y. [9] [10] The vaccines are between 85 and 100% effective for at least two years. [9]
The FDA accepts for review Sanofi's (SNY) BLA for MenQuadfi, a meningococcal vaccine candidate, presently under development to prevent meningococcal meningitis.
Brudziński's sign or a Brudziński sign is any of three medical signs, all of which may occur in meningitis or meningism. All three are named after Józef Brudziński . [ 1 ] In English, the name is often written without the diacritic (like many borrowed words) (Brudzinski) and is pronounced / b r uː ˈ dʒ ɪ n s k i / .
The classic triad of diagnostic signs consists of neck stiffness, sudden high fever, and altered mental status; however, all three features are present in only 44–46% of bacterial meningitis cases. [16] [17] If none of the three signs are present, acute meningitis is extremely unlikely. [17]
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