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  2. Dimenhydrinate - Wikipedia

    en.wikipedia.org/wiki/Dimenhydrinate

    Diphenhydramine is the primary constituent of dimen­hydrinate and dictates the primary effect. The main differences relative to pure diphen­hydramine are a lower potency due to being combined with 8-chloro­theo­phylline (by weight, dimen­hydrinate is between 53% and 55.5% diphen­hydramine) [10] and the fact that the stimulant properties of 8-chloro­theo­phylline help reduce the side ...

  3. Meclizine - Wikipedia

    en.wikipedia.org/wiki/Meclizine

    Some common side effects such as drowsiness, dry mouth, and tiredness may occur. Meclizine has been shown to have fewer dry mouth side effects than the traditional treatment for motion sickness, transdermal scopolamine. [16] A very serious allergic reaction to this drug is unlikely, but immediate medical attention should be sought if it occurs.

  4. Diphenhydramine - Wikipedia

    en.wikipedia.org/wiki/Diphenhydramine

    Diphenhydramine, sold under the brand name Benadryl among others, is an antihistamine and sedative.It is a first-generation H 1-antihistamine and it works by blocking certain effects of histamine, which produces its antihistamine and sedative effects.

  5. 8-Chlorotheophylline - Wikipedia

    en.wikipedia.org/wiki/8-Chlorotheophylline

    Diphenhydramine reduces nausea but causes drowsiness, and the stimulant properties of 8-Chlorotheophylline help reduce that side effect. [2] Despite being classified as a xanthine stimulant, 8-chlorotheophylline can generally not produce any locomotor activity above control in mice and does not appear to cross the blood-brain barrier well.

  6. Cinnarizine/dimenhydrinate - Wikipedia

    en.wikipedia.org/wiki/Cinnarizine/dimenhydrinate

    "Treatment of vertigo due to acute unilateral vestibular loss with a fixed combination of cinnarizine and dimenhydrinate: a double-blind, randomized, parallel-group clinical study". Clin Ther . 26 (6): 866– 77.

  7. Excessive daytime sleepiness - Wikipedia

    en.wikipedia.org/wiki/Excessive_daytime_sleepiness

    Causes Narcolepsy , idiopathic hypersomnia , circadian rhythm sleep disorder , sleep apnea , others Excessive daytime sleepiness ( EDS ) is characterized by persistent sleepiness and often a general lack of energy, even during the day after apparently adequate or even prolonged nighttime sleep.

  8. Antiemetic - Wikipedia

    en.wikipedia.org/wiki/Antiemetic

    Dimenhydrinate (Gravol, Dramamine) Doxylamine (Bonjesta, Unisom) Mirtazapine (Remeron) is an antidepressant that also has antiemetic effects. [5] [6] It is a potent histamine H1 receptor antagonist, K i =1.6 nM, [7] and also exhibits notable 5-HT 3 antagonism. [6] Meclizine (Bonine, Antivert)

  9. Cinnarizine - Wikipedia

    en.wikipedia.org/wiki/Cinnarizine

    However, due to increased levels of drowsiness caused by the medication, it is generally of limited use in pilots and aircrew who must be dependably alert. [ 6 ] Additionally, cinnarizine can be used in scuba divers without an increased risk of central nervous system oxygen toxicity which can result in seizures, and is a high risk in closed ...