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Heat is applied by baking in a dry heat oven that is designed specifically for the depyrogenation process. Although endotoxins are relatively thermally stable, sufficient heating (250 °C for 30 min) results in a 3-log reduction of endotoxin levels. Due to the high temperature levels, this method is also not suitable when purifying proteins.
Z-value is a term used in microbial thermal death time calculations. It is the number of degrees the temperature has to be increased to achieve a tenfold (i.e. 1 log 10) reduction in the D-value. The D-value of an organism is the time required in a given medium, at a given temperature, for a ten-fold reduction in the number of organisms.
Time-Temperature-Transformation diagram for two steels: one with 0.4% wt. C (red line) and one with 0.4% wt. C and 2% weight Mn (green line). P = pearlite, B = bainite and M = martensite. Isothermal transformation diagrams (also known as time-temperature-transformation ( TTT ) diagrams ) are plots of temperature versus time (usually on a ...
The main feature of thermodynamic diagrams is the equivalence between the area in the diagram and energy. When air changes pressure and temperature during a process and prescribes a closed curve within the diagram the area enclosed by this curve is proportional to the energy which has been gained or released by the air.
An orthographic projection of the 3D p–v–T graph showing pressure and temperature as the vertical and horizontal axes collapses the 3D plot into the standard 2D pressure–temperature diagram. When this is done, the solid–vapor, solid–liquid, and liquid–vapor surfaces collapse into three corresponding curved lines meeting at the ...
In thermodynamics, a temperature–entropy (T–s) diagram is a thermodynamic diagram used to visualize changes to temperature (T ) and specific entropy (s) during a thermodynamic process or cycle as the graph of a curve. It is a useful and common tool, particularly because it helps to visualize the heat transfer during a process.
Holloman and Jaffe determined the value of C experimentally by plotting hardness versus tempering time for a series of tempering temperatures of interest and interpolating the data to obtain the time necessary to yield a number of different hardness values. This work was based on six different heats of plain carbon steels with carbon contents ...
In thermodynamics, the Helmholtz free energy (or Helmholtz energy) is a thermodynamic potential that measures the useful work obtainable from a closed thermodynamic system at a constant temperature . The change in the Helmholtz energy during a process is equal to the maximum amount of work that the system can perform in a thermodynamic process ...