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Its use is advised against in people being concomitantly treated with: [13] [3] [5] [6] [21] [22] ACE inhibitors like captopril , enalapril , lisinopril , perindopril , and ramipril due to the potential for additive hyperkalaemic effects [ 5 ]
Brucellosis [4] is a zoonosis caused by ingestion of unpasteurized milk from infected animals, or close contact with their secretions. [5] It is also known as undulant fever, Malta fever, and Mediterranean fever. [6] The bacteria causing this disease, Brucella, are small, Gram-negative, nonmotile, nonspore-forming, rod-shaped (coccobacilli ...
One study has shown the allergic reaction rate to be about 3.0% over 359 courses of therapy. [11] Of the allergic reactions, skin rashes, eosinophilia and drug fever were the most common, while serious reactions were less common. Sulfamethoxazole is contraindicated in people with a known hypersensitivity to trimethoprim or sulfonamides. [9]
Brucella can also target the male reproductive tract. [7] Globally, an estimated 500,000 cases of brucellosis occur each year. [7] Malta fever was a major health problem to British troops in Malta in the 19th and early 20th centuries, resulting in over 6000 cases and 574 deaths. [9]
Over-the-counter (OTC) drugs are medicines sold directly to a consumer without a requirement for a prescription from a healthcare professional, [1] as opposed to prescription drugs, which may be supplied only to consumers possessing a valid prescription.
Brucella melitensis is a Gram-negative coccobacillus bacterium from the Brucellaceae family. The bacterium causes ovine brucellosis, along with Brucella ovis. Humans can become infected if they have contact with an infected animal or its byproducts. Animals acquire B. melitensis by venereal transmission. [1]