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Solar urticaria is an immunoglobulin E-mediated hypersensitivity that can be introduced through primary or secondary factors, or induced by exogenous photosensitization. [15] [16] Primary SU is believed to be a type I hypersensitivity (a mild to severe reaction to an antigen including anaphylaxis) in which an antigen, or substance provoking an immune response, is "induced by UV or visible ...
Over-the-counter vitamin C, 1000 mg daily, increases histamine degradation and removal. [8] [further explanation needed] While cromoglycate, which prevents histamine from being released from mast cells, is used topically in rhinitis and asthma, it is not effective orally for treating chronic urticaria. [citation needed]
One of the most prevalent forms of adverse drug reactions is cutaneous reactions, [1] with drug-induced urticaria ranking as the second most common type, preceded by drug-induced exanthems. [2] Urticaria, commonly known as hives , manifests as weals, itching, burning, redness, swelling, and angioedema —a rapid swelling of lower skin layers ...
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However, the understanding of urticaria as an autoimmune condition is a relatively recent development in medical history. [14] The term autoimmune urticaria refers to a subset of chronic spontaneous urticaria (CSU) cases where the immune system appears to play a significant role. This understanding began to evolve in the mid to late 20th ...
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Other similar appearing conditions are solar urticaria, which has a shorter duration, the eczema-like condition, photosensitive dermatitis, [2] and photosensitivity drug reaction. [9] Prickly heat, which is caused by warm weather or heat is not the same as PLE. [5] Photosensitivity is also found in some of the porphyrias.
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