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Macular edema; Other names: Macular oedema, [1] familial macular edema: A 61-year-old man with medical history of type 2 diabetes that presents a macular edema, evidenced by an OCT (the edema marked with arrows). The central image is a 3D reconstruction of the retinal thickness (the edema is coloured in red). Specialty
The American Academy of Ophthalmology practice guidelines recommend laser coagulation for people who have both mild to moderate nonproliferative diabetic retinopathy (NPDR) and clinically significant macular edema outside the fovea; treatment with anti-VEGF drugs is better than laser coagulation for clinically significant macular edema in the fovea. [1]
Findings include delayed venous filling, hypofluorescence caused by hemorrhage and capillary nonperfusion, dilation and tortuosity of veins, leakage due to neovascularization and macular edema. Optical coherence tomography is an adjunctive test in branch retinal vein occlusion. Macular edema is commonly seen on optical coherence tomography exams.
Macular edema is the most common cause of vision loss in people with diabetic retinopathy. [ 5 ] The repeated processes of blood vessel growth, swelling, and scarring can eventually cause retinal detachment , which manifests as the sudden appearance of dark floating spots, flashes of light, or blurred vision.
Ranibizumab, sold under the brand name Lucentis among others, is a monoclonal antibody fragment created from the same parent mouse antibody as bevacizumab.It is an anti-angiogenic [16] that is approved to treat the "wet" type of age-related macular degeneration (AMD, also ARMD), diabetic retinopathy, and macular edema due to branch retinal vein occlusion or central retinal vein occlusion.
Replacement of the lens as treatment for cataract can cause pseudophakic macular edema (‘pseudophakia’ means ‘replacement lens’). This could occur as the surgery involved sometimes irritates the retina (and other parts of the eye) causing the capillaries in the retina to dilate and leak fluid into the retina.