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Tofacitinib, sold under the brand Xeljanz among others, is a medication used to treat rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, polyarticular course juvenile idiopathic arthritis, and ulcerative colitis. [8] [9] [10] It is a janus kinase (JAK) inhibitor, [8] [9] discovered and developed by the National Institutes of ...
Rheumatism [2] /ˈruməˌtɪzəm/ or rheumatic disorders are conditions causing chronic, often intermittent pain affecting the joints or connective tissue. [3] Rheumatism does not designate any specific disorder, but covers at least 200 different conditions, including arthritis and "non-articular rheumatism", also known as "regional pain syndrome" or "soft tissue rheumatism".
Osteoarthritis is the most common form of arthritis, affecting about 237 million people or 3.3% of the world's population, as of 2015. [4] [12] It becomes more common as people age. [1] Among those over 60 years old, about 10% of males and 18% of females are affected. [2] Osteoarthritis is the cause of about 2% of years lived with disability. [12]
An estimated 24 percent of all adults in the U.S. (or 58.5 million) have arthritis, according to the Centers for Disease Control and Prevention. It’s even the leading cause of work disability.
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