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Oral cancer, also known as oral cavity cancer, tongue cancer or mouth cancer, is a cancer of the lining of the lips, mouth, or upper throat. [6] In the mouth, it most commonly starts as a painless red or white patch , that thickens, gets ulcerated and continues to grow.
Mucoepidermoid carcinomas of the salivary and bronchial glands are characterized by a recurrent t(11;19)(q21;p13) chromosomal translocation resulting in a MECT1-MAML2 fusion gene. [5]
Head and neck cancer is a general term encompassing multiple cancers that can develop in the head and neck region. These include cancers of the mouth, tongue, gums and lips (oral cancer), voice box (), throat (nasopharyngeal, oropharyngeal, [1] hypopharyngeal), salivary glands, nose and sinuses.
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Partners of patients with HPV-positive oropharyngeal cancer do not seem to have elevated oral HPV infection compared with the general population. [251] In Australia the incidence of HPV-associated OPC was 1.56 cases per 100,000 males/year (2001–2005), rising from 19% (1987–90) to 47% (2001–05) and 63.5% (2006–2010).