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Ranitidine, previously sold under the brand name Zantac [a] among others, is a medication used to decrease stomach acid production. [12] It was commonly used in treatment of peptic ulcer disease, gastroesophageal reflux disease, and Zollinger–Ellison syndrome. [12] It can be given by mouth, injection into a muscle, or injection into a vein.
Glaxo refined the model further by replacing the imidazole-ring of cimetidine with a furan-ring with a nitrogen-containing substituent, and in doing so developed ranitidine, which was found to have a much better tolerability profile (i.e. fewer adverse drug reactions), longer-lasting action, and ten times the activity of cimetidine.
Zantac can refer to either of two different H 2 antagonists used to reduce gastric acid secretion: Ranitidine , prior to its 2020 withdrawal from the market Famotidine , following the withdrawal of ranitidine
No reliable studies link Zantac use to cancer, Cheffo said, a view shared by all the defendants. Instead, he said, plaintiffs rely on a finding that Zantac's active ingredient, ranitidine, can ...
Sanofi discontinued the ranitidine formulation of Zantac, and the new formulation, Zantac 360, is made with a different active ingredient.
Sanofi has sold over-the-counter Zantac in the U.S. and Canada since 2017. It is pulling the drug off shelves after previous recalls by some manufacturers of generic versions of the drug.