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Cell Collective [3] is a modeling software that enables one to house dynamical biological data, build computational models, stimulate, break and recreate models. The development is led by Tomas Helikar, [4] a researcher within the field of computational biology. It is designed for biologists, students learning about computational biology ...
Cell-based models are mathematical models that represent biological cells as discrete entities. Within the field of computational biology they are often simply called agent-based models [1] of which they are a specific application and they are used for simulating the biomechanics of multicellular structures such as tissues. to study the influence of these behaviors on how tissues are organised ...
Cell Transmission Model (CTM) is a popular numerical method proposed by Carlos Daganzo [1] to solve the kinematic wave equation. [ 2 ] [ 3 ] Lebacque [ 4 ] later showed that CTM is the first order discrete Godunov approximation.
[72] [73] [74] The model consists of a cascade of a receptor layer model and a spiking neuron model, as shown in Fig 4. The connection between the external stimulus to the spiking probability is made in two steps: First, a receptor cell model translates the raw external stimulus to neurotransmitter concentration, and then, a spiking neuron ...
The state of each cell in a totalistic cellular automaton is represented by a number (usually an integer value drawn from a finite set), and the value of a cell at time t depends only on the sum of the values of the cells in its neighborhood (possibly including the cell itself) at time t − 1.
where i, j are lattice sites, σ i is the cell at site i, τ(σ) is the cell type of cell σ, J is the coefficient determining the adhesion between two cells of types τ(σ),τ(σ'), δ is the Kronecker delta, v(σ) is the volume of cell σ, V(σ) is the target volume, and λ is a Lagrange multiplier determining the strength of the volume ...
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By the 1950s, cell biologists verified the existence of plasma membranes through the use of electron microscopy (which accounted for higher resolutions). J. David Robertson used this method to propose the unit membrane model. [4] Basically, he suggested that all cellular membranes share a similar underlying structure, the unit membrane. Using ...