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Paget's disease of bone is the second most common metabolic bone disorder, after osteoporosis. [37] The overall prevalence and severity of Paget's disease are decreasing; the cause for these changes is unclear. [38] Paget's disease is rare in people less than 55 years of age, [7] and the prevalence increases with age. [38]
Urinalysis, a portmanteau of the words urine and analysis, [1] is a panel of medical tests that includes physical (macroscopic) examination of the urine, chemical evaluation using urine test strips, and microscopic examination.
Elevated levels are also associated with diabetes, hypertension, and cardiovascular disease; it was found that elevated levels are associated with elevated serum C-reactive protein (CRP), which could reflect an inflammatory and atherogenic milieu, possibly an alternative cause for elevated serum alkaline phosphatase.
A standard urine test strip may comprise up to 10 different chemical pads or reagents which react (change color) when immersed in, and then removed from, a urine sample.The test can often be read in as little as 60 to 120 seconds after dipping, although certain tests require longer.
The highest levels of acid phosphatase are found in metastasized prostate cancer. Diseases of the bone, such as Paget's disease or hyperparathyroidism, diseases of blood cells, such as sickle-cell disease or multiple myeloma or lysosomal storage diseases, such as Gaucher's disease, will show moderately increased levels.
A urine test is any medical test performed on a urine specimen. The analysis of urine is a valuable diagnostic tool because its composition reflects the functioning of many body systems, particularly the kidneys and urinary system , and specimens are easy to obtain. [ 1 ]
James Paget in 1870 James Paget in 1881 "Surgery" Caricature by Spy published in Vanity Fair in 1876. Sir James Paget, 1st Baronet FRS HFRSE (11 January 1814 – 30 December 1899) (/ ˈ p æ dʒ ə t /, rhymes with "gadget") was an English surgeon and pathologist who is best remembered for naming Paget's disease [1] and who is considered, together with Rudolf Virchow, as one of the founders of ...
Extramammary Paget's disease (EMPD) is a rare and slow-growing cancer, which occurs within the epithelial tissues [1] and accounts for 6.5% of all Paget's disease. [2] This disease presents similarly to the more conventional form of mammary Paget's disease (MPD). [ 3 ]