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Methemoglobinemia, or methaemoglobinaemia, is a condition of elevated methemoglobin in the blood. [2] Symptoms may include headache, dizziness, shortness of breath, nausea, poor muscle coordination, and blue-colored skin (cyanosis). [ 2 ]
It is recommended that treatment with methylene blue requires two doses before being deemed ineffective. If symptoms of methemoglobinemia are still present after the second dosage, alternative treatments, including ascorbic acid, exchange transfusion, and hyperbaric oxygen therapy, can be considered. However, no additional antidote has been ...
The structure of cytochrome b5 reductase, the enzyme that converts methemoglobin to hemoglobin. [1]Methemoglobin (British: methaemoglobin, shortened MetHb) (pronounced "met-hemoglobin") is a hemoglobin in the form of metalloprotein, in which the iron in the heme group is in the Fe 3+ state, not the Fe 2+ of normal hemoglobin.
The first-line treatment for severe methemoglobinemia is methylene blue, a medication that will reduce methemoglobin in the blood. This is possible because methylene blue oxidizes NADPH , which in turn can convert methemoglobin back to hemoglobin.
Symptoms: Chronic anemia: ... termination of pregnancy: Treatment: ... Methemoglobinemia is a condition caused by elevated levels of methemoglobin in the blood.
Anemia in pregnancy is a decrease in the total red blood cells (RBCs) or hemoglobin in the blood during pregnancy. Anemia is an extremely common condition in pregnancy world-wide, conferring a number of health risks to mother and child. [ 2 ]
Hemoglobin M disease is often not life-threatening and treatment is not necessary. There is no existing effective treatment, including methylene blue (MB) and ascorbic acid used in treating acquired methemoglobinemia. [12] MB is an oxidant and it is not used to treat hemoglobin M disease. They are prone to develop symptomatic methemoglobinemia ...
Treatments for nutritional anemia includes replacement therapy is used to elevate the low levels of nutrients.[1] Diet improvement is a way to combat nutritional anemia and this can be done by taking dietary supplements such as iron, folate, and Vitamin B12.[2] These supplements are available over-the-counter however, a doctor may prescribe ...