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Moxidectin is an anthelmintic drug used in animals to prevent or control parasitic worms , such as heartworm and intestinal worms, in dogs, cats, horses, cattle, sheep and wombats. [4] Moxidectin kills some of the most common internal and external parasites by selectively binding to a parasite's glutamate-gated chloride ion channels .
Frunevetmab is a cat-specific monoclonal antibody (a type of protein) designed to recognize and attach to a protein called nerve growth factor that is involved in the regulation of pain. [3] When frunevetmab binds to nerve growth factor, it prevents the pain signal from reaching the brain.
Moxidectin is also available in both a six-month and 12-month sustained-release injection, ProHeart 6 and ProHeart 12, respectively, administered by veterinarians. This injectable form of moxidectin was taken off the market in the United States due to safety concerns in 2004, but the FDA returned a newly formulated ProHeart 6 to the market in 2008.
These recommendations take into account considerations for the efficacy and duration of immunity (DOI) [1] of available vaccines; environmental risks and likelihood of exposure; the specific needs and risks associated with age and overall health status of different cats and cat populations; and socioeconomic limitations.
Wyeth also made its first licensing deal, acquiring an antibiotic for arthritis vaccine research. [ citation needed ] In 1941, the US entered World War II , and Wyeth shipped typical wartime drugs such as sulfa bacteriostatics, blood plasma , typhus vaccine, quinine , and atabrine tablets.
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