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Microsporidiosis is an opportunistic intestinal infection that causes diarrhea and wasting in immunocompromised individuals (HIV, for example). It results from different species of microsporidia , a group of microbial (unicellular) fungi.
The named species of microsporidia usually infect one host species or a group of closely related taxa. Approximately 10 percent of the known species are parasites of vertebrates — several species, most of which are opportunistic, can infect humans, in whom they can cause microsporidiosis.
Enterocytozoon bieneusi, commonly known as microsporidia, is a unicellular, obligate intracellular eukaryote.Their life cycle includes a proliferative merogonic stage, followed by a sporogonic stage resulting in small, environmentally resistant, infective spores, which is their transmission mode.
Microsporidia is a group of fungi that infect species across the animal kingdom, one species of which can cause microsporidiosis in immunocompromised human hosts. [ 30 ] Pneumocystis jirovecii (formerly known as Pneumocystis carinii ) is a fungus that causes pneumocystis pneumonia , a respiratory infection.
American-funded aid efforts to tackle diseases such as malaria, as well as preventing newborn baby deaths and treating severe malnutrition, should resume, according to a memo from the United ...
Encephalitozoon intestinalis is a parasite. [1] It can cause microsporidiosis. [2]It is notable as having one of the smallest genome among known eukaryotic organisms, containing only 2.25 million base pairs. [3]
Only the development within gilthead sea bream is currently known. [1] Since some of the closest relatives of E. nucleophila infect crustaceans (e.g., Enterospora canceri or E. hepatopenaei), and some of them have heteroxenous cycles alternating between crustacean and fish hosts (e.g., Desmozoon lepeophtheri [3] [citation needed]), a similar alternating cycle could occur for E. nucleophila.
Fumagillin has been used in the treatment of microsporidiosis. [8] [9] It is also an amebicide.[10]Fumagillin can block blood vessel formation by binding to an enzyme methionine aminopeptidase 2 [11] and for this reason, the compound, together with semisynthetic derivatives, are investigated as an angiogenesis inhibitor [12] in the treatment of cancer.