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The drug — the brand name for the GLP-1 agonist semaglutide — “significantly reduced weekly alcohol craving,” according to a study published Wednesday, Feb. 12, in the Journal of the ...
The study, led by researchers at the Veterans Affairs St. Louis Health Care System, found that use of these GLP-1s, as they are classified, was associated with reduced risks of a number of health ...
A new study compares the benefits and risks of taking GLP-1 medications for weight loss, including risks of dementia, addiction, heart disease, and gastrointestinal problems, among others.
The initial product GLP-1 (1–37) is susceptible to amidation and proteolytic cleavage, which gives rise to the two truncated and equipotent biologically active forms, GLP-1 (7–36) amide and GLP-1 (7–37). Active GLP-1 protein secondary structure includes two α-helices from amino acid position 13–20 and 24–35 separated by a linker region.
GLP1 poly-agonist peptides [1] are a class of drugs that activate multiple peptide hormone receptors including the glucagon-like peptide-1 (GLP-1) receptor.These drugs are developed for the same indications as GLP-1 receptor agonists—especially obesity, type 2 diabetes, and non-alcoholic fatty liver disease.
In one review of 14 studies, researchers found GLP-1 agonists led to an average weight loss difference of 4-6.2 percent in people with diabetes versus 6.1-17.4 percent in people without diabetes ...
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