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Medium-chain acyl-CoA dehydrogenase deficiency (MCAD deficiency or MCADD) is a disorder of fatty acid oxidation that impairs the body's ability to break down medium-chain fatty acids into acetyl-CoA. The disorder is characterized by hypoglycemia and sudden death without timely intervention, most often brought on by periods of fasting or vomiting.
For example, in Australia, suicide is second only to motor vehicle accidents as its leading cause of death for adolescents and young adults aged 15 to 25. [ 2 ] In the United States, according to the National Institute of Mental Health , suicide is the second leading cause of death for adolescents between the ages of 10 and 14, and the third ...
In addition to the fetal complications, they can also cause complications for the mother during pregnancy. [4] Examples include: Mitochondrial trifunctional protein deficiency (MTPD) [3] MCADD, LCHADD, and VLCADD [5] Schematic demonstrating mitochondrial fatty acid beta-oxidation and effects of LCHAD deficiency
There have been many studies in multiple countries about "street children"—youth who have run away and are presently homeless—showing that they have a high risk of taking illicit drugs, developing sexually transmitted infections (STIs), unintended pregnancy, depression, suicide attempts, and sexual exploitation. [7]
The suicide rate among Black youth has been increasing along with the number of suicide attempts and the severity of those attempts, according to the most recent Youth Risk Behavior Survey from ...
SUDC is rare, with a reported incidence in the United States of 1.2 deaths per 100,000 children, compared to 54 deaths per 100,000 live births for SIDs. There are approximately 400 deaths per year of SUDC in the U.S, with over 200 of these cases being the children aged 1–4 years. [3] SUDC deaths have occurred at the following sites: [4]
Children as young as 12 can seek euthanasia in the Netherlands, although patients younger than 16 years old need parental consent to do so. In 2017, the country saw a reported 6,585 deaths by ...
Suicide was the 5th leading cause of death in girls between 2008 and 2022, moving up from being the 11th leading cause between 2001 and 2007. Suicide rates among preteen girls rose to 4.15 per ...