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Given the success of the IPI for intermediate grade lymphomas, an effort was undertaken to develop a similar prognostic index for the most common low-grade lymphoma, follicular lymphoma. The prognostic factors that emerged from this were: age, stage, number of lymph node areas involved, serum hemoglobin level, and serum LDH. [3]
Waldenström macroglobulinemia is an "indolent lymphoma" ... An additional predictive factor is elevated serum lactate dehydrogenase (LDH). [85] Epidemiology
LDH-5 (4M)—in the liver and striated muscle, [5] also present in the brain [4] LDH-2 is usually the predominant form in the serum. An LDH-1 level higher than the LDH-2 level (a "flipped pattern") suggests myocardial infarction (damage to heart tissues releases
Tumor markers can be determined in serum or rarely in urine or other body fluids, often by immunoassay, but other techniques such as enzyme activity determination are sometimes used. Assaying tumor markers were significantly improved after the creation of ELISA and RIA techniques and the advancement of monoclonal antibodies in the 1960s ...
These factors include elevated baseline serum creatinine, kidney failure, dehydration, and other issues affecting urinary flow or the acidity of urine. [14] Chemotherapy characteristics: Chemo-sensitive tumors, such as lymphomas, carry a higher risk for the development of tumor lysis syndrome.
Diffuse large B-cell lymphoma type, Hodgkin's lymphoma type Prognosis Poor, though it depends on the type of the leukemia or lymphoma that was initially present and the one it turns into, as well as the genetic mutations and translocations and deletions of the tumor, the person's sex, age, and comorbidities, the results of blood tests, the ...
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