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A recent large-scale study found that severe depression in patients with bipolar disorder responds no better to a combination of antidepressant medications and mood stabilizers than it does to mood stabilizers alone and that antidepressant use does not hasten the emergence of manic symptoms in patients with bipolar disorder. [40]
Antidepressants by themselves shouldn’t be used to treat bipolar disorder because they elevate the risk of triggering a manic episode. (Learn more about Antidepressants .)
This brings some risks, however, as antidepressants can induce mania, [19] psychosis, [20] and other disturbing problems in people with bipolar disorder—in particular, when taken alone. The risk of antidepressant-induced mania when given to patients concomitantly on antimanic agents is not known for certain but may still exist. [21]
Treatment of bipolar disorder using antidepressants may carry a risk of affective switches where a person switches from depression to manic or hypomanic phases or mixed states. [22] There may also be a risk of accelerating cycling between phases when antidepressants are used in bipolar disorder.
Escitalopram, a less recognizable term, is the generic name for this common prescription antidepressant. ... bipolar disorder, premenstrual dysphoric disorder (PMDD), post-traumatic stress ...
Medications for Depression: An Overview. Antidepressants are a class of medications used very commonly to treat depression. In fact, nearly 13 percent of people 12 and over in the U.S. used ...
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