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For 95–97% of cases, infection is resolved after one dose of metronidazole. [26] [35] Studies suggest that 4–5% of trichomonas cases are resistant to metronidazole, which may account for some "repeat" cases. [33] [9] Without treatment, trichomoniasis can persist for months to years in women, and is thought to improve without treatment in ...
Trichomonas vaginalis from a vaginal swab. This is a heavy infection; there were probably thousands of trichomonads in the vagina. Alfred Francois Donné (1801–1878) was the first to describe a procedure to diagnose trichomoniasis through "the microscopic observation of motile protozoa in vaginal or cervical secretions" in 1836.
Metronidazole, sold under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication. [10] It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. [10]
An antitrichomonal agent is an antiprotozoal agent that acts on trichomonas parasites. [1] Examples include: [2] furazolidone; nifuratel; nimorazole; ornidazole ...
However, in women with trichomonas the organism is typically detected in only 60-80% of cases. [28] Other testing, including a culture of the discharge or a PCR assay, are more likely to detect the organism. [28] Treatment is with a one time dose of oral antibiotics, most commonly metronidazole or tinidazole. [28]
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