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Signs of hyperestrogenism may include heightened levels of one or more of the estrogen sex hormones (usually estradiol and/or estrone), lowered levels of follicle-stimulating hormone and/or luteinizing hormone (due to suppression of the hypothalamic–pituitary–gonadal axis by estrogen), and lowered levels of androgens such as testosterone (generally only relevant to males). [1]
Hypoestrogenism, or estrogen deficiency, refers to a lower than normal level of estrogen. It is an umbrella term used to describe estrogen deficiency in various conditions. Estrogen deficiency is also associated with an increased risk of cardiovascular disease, [1] and has been linked to diseases like urinary tract infections [2] and osteoporosis.
ICD-10 is the 10th revision of the International Classification of Diseases (ICD), a medical classification list by the World Health Organization (WHO). It contains codes for diseases, signs and symptoms, abnormal findings, complaints, social circumstances, and external causes of injury or diseases. [1]
An estrogen-dependent condition can be that relating to the differentiation in the steroid sex hormone that is associated with the female reproductive system and sex characteristics. [1] These conditions can fall under the umbrella of hypoestrogenism, hyperestrogenim, or any sensitivity to the presence of estrogen in the body.
[9] [10] Normal total testosterone levels depend on the man's age but generally range from 240 to 950 ng/dL (nanograms per deciliter) or 8.3–32.9 nmol/L (nanomoles per liter). [ 11 ] According to American Urological Association, the diagnosis of low testosterone can be supported when the total testosterone level is below 300 ng/dl. [ 12 ]
This leads to decreased estrogen production and symptoms of atrophic vaginitis. [6] Hypothalamic-Pituitary Disorders: These disorders directly affect the hypothalamus or pituitary gland, disrupting hormone production. [6] [10] Anti-Estrogen Medications: Medications such as Danazol or Leuprolide can lower estrogen levels. [6] [11]
Hypergonadism is a condition where there is a hyperfunction of the gonads. [1] It can manifest as precocious puberty, and is caused by abnormally high levels of testosterone or estrogen, crucial hormones for sexual development.
Although "pseudohermaphroditism" persisted in the International Classification of Diseases, Versions 9 (ICD-9) and 10 (ICD-10) as 752.7 (Indeterminate sex and pseudohermaphroditism) [19] and Q56 (Interdeterminate sex and pseudohermaphroditism), [20] it has since been removed in the eleventh version (ICD-11), in favor of LD2A.Y (Other specified ...