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Bethanechol is a parasympathomimetic choline carbamate that selectively stimulates muscarinic receptors without any effect on nicotinic receptors. Unlike acetylcholine , bethanechol is not hydrolyzed by cholinesterase and will therefore have a long duration of action.
Several recent studies of children have found levels that exceed the EPAs suggested safe limit figure. [174] Infants fed with liquid formula are among the most exposed, and those fed formula from polycarbonate bottles can consume up to 13 micrograms of bisphenol A per kg of body weight per day (μg/kg/day; see table below). [197]
Bethanechol is a muscarinic agonist.It is included in the therapy for underactive bladder with poor contraction of detrusor muscle. [2] Since contraction of detrusor muscle in the bladder is controlled by the parasympathetic nervous system, Bethanechol can bind to muscarinic receptors to stimulate activation of the parasympathetic nervous system and restore contraction of detrusor muscle.
Bethanechol +++--Used in bladder and gastrointestinal hypotonia. Muscarine +++--Natural alkaloid found in certain mushrooms. Cause of one form of mushroom poisoning Nicotine-+++-Natural alkaloid found in the tobacco plant. Pilocarpine ++--Used in glaucoma. Oxotremorine ++ + [12]-Used in research to induce symptoms of Parkinson's disease.
Many antidepressants seem to have sexual side effects. Can anything be done about those side-effects? Both lowered sexual desire and difficulties having an orgasm, in both men and women, are particularly a problem with the selective serotonin re-uptake inhibitors (Prozac, Zoloft, Paxil and Luvox), and the monoamine oxidase inhibitors (Nardil ...
The WHO Model List of Essential Medicines for Children (aka Essential Medicines List for Children [1] or EMLc [1]), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe in children up to twelve years of age to meet the most important needs in a health system.
A parasympathomimetic drug, sometimes called a cholinomimetic drug [1] or cholinergic receptor stimulating agent, [2] is a substance that stimulates the parasympathetic nervous system (PSNS).
"Anti-cholinergic" side-effects, including urinary hesitancy/retention, may be treated/reversed with bethanechol and/or other acetylcholine-agonists. [48] [49] [50] Bethanechol may also be able to alleviate the sexual-dysfunction symptoms which may occur in the context of tricyclic-antidepressant treatment. [51] [52] [53]