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The most significant effect is accumulation of calcium oxalate crystals in the kidneys which causes kidney damage leading to oliguric or anuric acute kidney failure. [7] The rate-limiting step in this cascade is the conversion of glycolic to glyoxylic acid. [14] Accumulation of glycolic acid in the body is mainly responsible for toxicity. [15]
Some ways by which crystals form are precipitating from a solution, freezing, or more rarely deposition directly from a gas. Attributes of the resulting crystal depend largely on factors such as temperature, air pressure, cooling rate, and in the case of liquid crystals, time of fluid evaporation. Crystallization occurs in two major steps.
Ethane (US: / ˈ ɛ θ eɪ n / ETH-ayn, UK: / ˈ iː θ eɪ n / EE-thayn) is a naturally occurring organic chemical compound with chemical formula C 2 H 6. At standard temperature and pressure, ethane is a colorless, odorless gas. Like many hydrocarbons, ethane is isolated on an industrial scale from natural gas and as a petrochemical by ...
In principle, crystal formation can happen anywhere in the body. Well-known places are excretory organs where concentrations get high easily, like in the biliary and urinary tracts, but crystalline structures are also formed in intracellular and extracellular spaces of tissues, like within the arterial wall in atherosclerosis.
Biocrystallization is the formation of crystals from organic macromolecules by living organisms. [1] This may be a stress response, a normal part of metabolism such as processes that dispose of waste compounds, or a pathology. Template mediated crystallization is qualitatively different from in vitro crystallization.
Ethylene glycol (IUPAC name: ethane-1,2-diol) is an organic compound (a vicinal diol [7]) with the formula (CH 2 OH) 2. It is mainly used for two purposes: as a raw material in the manufacture of polyester fibers and for antifreeze formulations. It is an odorless, colorless, flammable, viscous liquid.
Vitrification is the progressive partial fusion of a clay, or of a body, as a result of a firing process. As vitrification proceeds, the proportion of glassy bond increases and the apparent porosity of the fired product becomes progressively lower. [3] [10] Vitreous bodies have open porosity, and may be either opaque or translucent. In this ...
Acid–base homeostasis is the homeostatic regulation of the pH of the body's extracellular fluid (ECF). [1] The proper balance between the acids and bases (i.e. the pH) in the ECF is crucial for the normal physiology of the body—and for cellular metabolism. [1]