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The loudness of the murmur does not correlate well with the severity of regurgitation. It may be followed by a loud, palpable P 2, [6] heard best when lying on the left side. [7] A third heart sound is commonly heard. [6] Patients with mitral valve prolapse may have a holosystolic murmur or often a mid-to-late systolic click and a late systolic ...
Mitral valve prolapse (MVP) is a valvular heart disease characterized by the displacement of an abnormally thickened mitral valve leaflet into the left atrium during systole. [4] It is the primary form of myxomatous degeneration of the valve.
Patients with a mitral valve prolapse are usually asymptomatic, but often have a classic heart murmur which includes a mid-systolic click, which is sometimes followed by a systolic murmur. The click is a result of the leaflet folding into the atrium and being suddenly stopped by the chordae tendineae.
Patients with mitral valve prolapse may have a mid-systolic click along with a murmur, referred to as apical late systolic murmur. [3] Early systolic clicks may also be present in some patients. [4] Aortic and pulmonary stenosis may cause an ejection click [5] immediately after S 1.
Shone’s syndrome is a rare disorder that is often detected in very young children. The children tend to show symptoms like fatigue, nocturnal cough, and reduced cardiac output by the age of two years. They also develop wheezing due to the exudation of fluid into the lungs. [1]
Valvular heart disease resulting from rheumatic fever is referred to as rheumatic heart disease. Acute rheumatic fever, which frequently manifests with carditis and valvulitis, [ 20 ] is a late sequela of Group A beta-hemolytic streptococcus infection in the throat, often lagging the initial infection by weeks to months. [ 21 ]
Almost all cases of mitral stenosis are due to disease in the heart secondary to rheumatic fever and the consequent rheumatic heart disease. [3] [5] Uncommon causes of mitral stenosis are calcification [6] [7] of the mitral valve leaflets, and as a form of congenital heart disease. It is the most common valvular heart disease in pregnancy. [8]
Lutembacher's syndrome is a very rare [1] form of congenital heart disease that affects one of the chambers of the heart (commonly the atria) as well as a valve (commonly the mitral valve). It is commonly known as both congenital atrial septal defect (ASD) and acquired mitral stenosis (MS) . [ 2 ]