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Side effects may include bleeding, most commonly from the nose, gastrointestinal tract (GI) or genitourinary system. [2] Compared to the risk of bleeding with warfarin use, direct factor Xa inhibitors have a higher risk of GI bleeding, but lower risk of bleeding in the brain . [ 2 ]
Apixaban is recommended by the National Institute for Health and Clinical Excellence for the prevention of stroke and systemic embolism in people with non-valvular atrial fibrillation and at least one of the following risk factors: prior stroke or transient ischemic attack, age 75 years or older, diabetes, or symptomatic heart failure.
A 2023 review stated that ongoing sexual dysfunction after SSRI discontinuation was possible, but that cause and effect were undetermined. [64] The 2023 review cautioned that reports of sexual dysfunction cannot be generalized to wider practice as they are subject to a "high risk of bias", but agreed with the EMA assessment that cautionary ...
Other anxiety disorders include obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, social anxiety disorder, and phobias. There are plenty of treatment options that ...
Fatigue and drowsiness are two of the most common side effects of sertraline, and if you’re using sertraline to treat depression, fatigue and tiredness can also be compounded by the effects of ...
Tricyclic antidepressants (TCAs) have anxiolytic effects; however, side effects are often more troubling or severe and overdose is dangerous. They are considered effective, but have generally been replaced by antidepressants that cause different adverse effects. Examples include imipramine, doxepin, amitriptyline, nortriptyline and desipramine ...
A 2020 systemic review found that the herb typically reduced anxiety in people, with no concerning side effects. “It should not replace professional medical treatment for anxiety disorders ...
The effect size (SMD) for improvement with placebo in trials of antidepressants for anxiety disorders is approximately 1.0, which is a large improvement in terms of effect size definitions. [45] In relation to this, most of the benefit of antidepressants for anxiety disorders is attributable to placebo responses rather than to the effects of ...
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